This talk hack is really designed for the movie maker (and storyteller) who films a lot of dialogue. When I film dialogue, I look for tone in talking/listening/reaction animations so that's I organized it. This hack does not have many submenus (2-3 at most). All of the selections have descriptions, or the best guess of what I think they look like, in order minimize ambiguity so you're not constantly replaying an animation to see what it looks like. Here is how the hack is organized:

Talk (straightforward talking, some moderate ones that would be ok for conversations; there may be some overlap in style but I didn't want one menu to be too long and the other short)
Moderate Talker (some body movement but not too cartoony)
Animated Talker (cartoony)
Argue Talker (self-explanatory)
Argue Listener (both defensive and concillatory)
Listen Negative (self-explanatory)
Listen (normal listening, not cartoony)
Reaction (postive and mild negative)
Reaction Neg (High) (reactions that are negative but dramatic)
Agree (normal to moderate)
Disagree (normal to moderate)
Topics (in-game topics, cartoony)
Talk String (includes 2 custom combination of debate talk animations, 4 custom combinations of the normal talking, animated animations, and moderate animation strings)
Misc (includes handslap guestures, speech whistle, pray- pulled from apologize, handshake)

For the handslap and handshake animations, you get 2 sims to chat and then cancel that out. Then pause and cue up whatever handslap animations (or handshake) you want for each sim. Then unpause. It might take a couple of takes because the sims switch the arm that they use but it will line up. If you're having trouble, try having only one sim run through the motions and then do both (you can usually synch them on the 2nd take).

This can be found in Hobbies...Miscellaneous and the picture is from AinD.